*Source: https://www.years.co/en/check-up-ab-40* Check-up from 40 # At 40, every marker counts. Identify risks before they become diagnoses. The most comprehensive health check from age 40 in Berlin. ApoB, hormone profile, insulin resistance, whole-body MRI: everything that genuinely matters after 40. Private practice, in a single day. Book an appointment - From €1,900 - Everything in one day - Private insurance reimbursement possible - Berlin-Charlottenburg ## What changes from 40, and what a check-up can do about it From 40 onwards, risks shift long before they cause symptoms: blood pressure, lipid metabolism, insulin sensitivity and body composition change over years, and all of it is measurable. The statutory German health examination covers blood pressure, blood glucose, cholesterol and a basic history; it remains the foundation. A check-up at YEARS goes deeper, with ApoB and Lp(a) rather than LDL alone, measured instead of estimated fitness, and a physician interpreting every finding. That this additional depth by itself lowers mortality is not established. What is established is that the underlying risk factors are treatable, and that they become visible earlier when you measure more precisely. How we classify procedures ## At 40 your body changes quietly — and on several fronts at once. Three biological processes start to become measurable in your forties. Identify them early and you have 30+ years to influence them. ### Cardiovascular plaque ApoB particles and Lp(a) have been depositing in your vessels since your thirties. By 40, early calcification is often already detectable — long before any symptom. Measuring early can often reverse what later can only be slowed. ### Hormonal change Oestrogen, testosterone, DHEA and thyroid values begin to shift. Symptoms such as loss of energy, poor sleep or muscle loss are rarely coincidental — they are often measurable hormone deficits. ### Metabolic drift Insulin resistance often begins 10-15 years before a diabetes diagnosis. The oral glucose tolerance test reveals early signs that standard fasting glucose misses. ## What we examine especially thoroughly from 40 onwards. More than 25 functional tests, 87 biomarkers and imaging — focused on the risks that start to surface in your forties. ### ApoB & Lp(a) The two most important cardiovascular risk markers — considerably more informative than LDL cholesterol alone. A standard check at a family doctor does not test for them. ### Complete hormone profile Oestrogen, testosterone, progesterone, DHEA-S, free T3/T4, diurnal cortisol profile. Detects subclinical deficits that affect energy and performance. ### Detecting insulin resistance early Oral glucose tolerance test with insulin measurement. Shows changes long before HbA1c becomes abnormal. ### Whole-body MRI (from Evolve) High-resolution imaging for early tumour indicators, aneurysms and organ changes — radiation-free, without contrast agent. ### VO2max & spiroergometry Your cardiorespiratory fitness is the strongest predictor of your life expectancy. We measure it precisely — and show where you stand for your age. ### Neurocognitive baseline Tests of memory and reaction performance create a reference value for the years ahead — important for early detection of dementia. ## Which programme suits you at 40? Core is the ideal entry point. Evolve and Ultimate add further depth for comprehensive prevention. Core Evolve Ultimate Price €1,900 €7,600 €16,900 Biomarkers 87 120+ 230+ ApoB & Lp(a) Hormone profile Whole-body MRI Liquid biopsy Genetics Microbiome analysis Price core €1,900 evolve €7,600 ultimate €16,900 Biomarkers core 87 evolve 120+ ultimate 230+ ApoB & Lp(a) core ✓ evolve ✓ ultimate ✓ Hormone profile core ✓ evolve ✓ ultimate ✓ Whole-body MRI core — evolve ✓ ultimate ✓ Liquid biopsy core — evolve ✓ ultimate ✓ Genetics core — evolve — ultimate ✓ Microbiome analysis core — evolve — ultimate ✓ Choose a programme & book ## Relevant diagnostics Whole-body MRI screening Early detection of organ and vascular changes Liquid biopsy Multi-cancer detection from a blood test — valuable from 40 Longevity medicine A scientific approach to healthy longevity Whole-body check-up What the term covers, what it costs and where its limits are ## Also of interest Health check from 50 Cancer screening, sarcopenia, bone health Check-up for women Hormones, breast, bones, cardiac risk Check-up for men Heart, prostate, testosterone, performance More on the full range: Health check Berlin overview ## Frequently asked questions about the check-up from 40 Why is 40 the right age for a comprehensive check-up? + From 40, cardiovascular risks (plaque formation), hormonal change and metabolic shifts begin — usually silently and without symptoms. Measuring early often lets you reverse with lifestyle changes what would later require medication. What about the statutory check-up from 35? + The statutory check from 35 covers only basic values (cholesterol, blood glucose, blood pressure). Important markers such as ApoB, Lp(a), hormone profile, insulin resistance, bone density and whole-body MRI are not included — precisely the values that become informative from 40 onwards. Which programme makes most sense for someone aged 40? + Core (€1,900) is the entry point with 87 biomarkers and functional tests. If you want the full picture once, including whole-body MRI and cancer liquid biopsy, choose Evolve (€7,600). Ultimate (€16,900) adds genetics and microbiome — sensible with a family history. Will private health insurance reimburse the check-up? + With many private insurers and policies, partial or full reimbursement is possible. We issue a detailed report with diagnostic codes that you can submit to your insurer. The exact reimbursement depends on your individual policy. How long does the check-up take? + A YEARS day takes 6 to 10 hours depending on the programme — everything in one day, in Berlin-Charlottenburg. Breakfast and lunch are included. You receive your detailed report within a week, often directly in a personal consultation on the same day. How often should I repeat the check-up? + From 40 we recommend an annual rhythm for the baseline values (Core), and Evolve or Ultimate every 2-3 years. That builds a longitudinal data set and lets you spot changes early. ## Start your next 40 years with clarity. Book your appointment in Berlin-Charlottenburg. Private practice, no referral needed. Book an appointment Or book a free introductory call