YEARS Evolve®

A rigorous, science-driven path to longer healthspan.

YEARS Evolve empowers you with deeper insights, ultra-personalized strategies, and year-round healthspan guidance.

YEARS Evolve®

EUR 7,600

May vary depending on individual needs.

  • Core Diagnostics + Whole Body MRI + Multi Cancer Screening
  • Extended lab panel with 120+ biomarkers
  • Cryopreservation of 70+ biological samples for potential future use
  • YEARS Performance Battery
  • Biannual physician-led check-in, continued monitoring and more
Toan Nguyen
“My check-up at YEARS showed me how far modern prevention can go today. Instead of brief consultations, there was real depth: a comprehensive look at my body, clearly explained and systematically evaluated.”
Toan NguyenFounder & Podcast Host

Decode Aging

Your Evolve® Journey

Pre-Visit Consultation

Pre-Visit Consultation

30 Minutes | Concierge Intake

Before your visit, our concierge team takes the time to understand your goals and priorities – tailoring your experience from the start.

Evolve® Clinic Visit

Evolve® Clinic Visit

9 Hours | Advanced Diagnostics

A full day of 30+ advanced assessments, including imaging, cardiovascular, metabolic, and molecular testing.

Risk Mapping & Strategic Planning

Risk Mapping & Strategic Planning

2 Weeks | In-depth Data Interpretation & Strategy Call

Our physician team meticulously analyses your data and reviews the findings with you in a focused strategy call.

Personalized Coaching

Personalized Coaching

Initial Session | Lifestyle Optimisation

A focused coaching session in nutrition and performance, with optional ongoing support to keep interventions effective.

Continuous Health Monitoring

Continuous Health Monitoring

Biannual | Healthspan Services

Receive tailored insights year-round through continuous monitoring and a biannual physician check-in.

Annual Reassessment

Annual Reassessment

Yearly | Progress Review & Strategic Update

Each year, key diagnostics are repeated to track progress, detect changes, and shape your long-term health trajectory.

Diagnostics

The foundation of our diagnostics translates epidemiological research into clinical practice. 25+ assessments and 80+ biomarkers – the basis for strategies to support your healthspan.

Cardiovascular AssessmentHigh-Resolution UltrasoundAI-based Full-Body Skin MappingComprehensive Lung Function Testing3D Body ScanAI-Assisted Retinal ImagingPerformance DiagnosticsNeurocognitive & Mental HealthSensory TestingBone Density MeasurementOral Glucose Tolerance Test (OGTT)

Expands the Core® lab panel to 120+ biomarkers across hormones, vitamins, inflammation, trace elements and functional markers. Systems medicine for deeper insights into your health.

Advanced Hormone ProfileCardiovascular & Metabolic MarkersInflammation & Functional HealthExtended Longevity PanelVitamins & Trace Elements

TruCheck is an advanced, non-invasive blood test for early detection of over 70 tumors, with specificity of 96–99 % and sensitivity of 65–89 % (stage-dependent) in the published validation studies. YEARS deliberately uses liquid biopsy as a research-adjacent and experimental procedure: it complements established cancer screening and does not replace it.

intelli TruCheck™intelli TruBlood™

The YEARS Evolve® MRI sequence provides high-resolution, radiation-free organ and tissue images that can support detection of hidden conditions (e.g. tumors, aneurysms, fatty liver or vascular anomalies). The YEARS whole-body MRI is used in an experimental, research-adjacent context and is interpreted accordingly.

Multi-Organ ScreenCardiovascular ConditionsNeurological DisordersOncological Screening

Led by our performance team: advanced analyses of fitness, mobility, balance and muscle strength – for long-term physical performance.

3D BodyscanningMotion AnalysisForce MeasurementCardiovascular FitnessPersonalized Plan

Concierge Services

All results are consolidated into your YEARS Health Report, visualised and clearly explained. Complex diagnostics become a clear picture of your body and potential risks.

Personal Risk ProfileIndividual Health StrategyProgress Analysis (from Year 2)

Together with your physician, your findings are translated into an individual prevention strategy aligned with your goals for long-term health and performance.

Physician-Led StrategyContinuous Therapy Management

With Evolve® you have ongoing access to our Healthspan Concierge. Whether new results, nutrition or training plan – our team supports you at all times.

10h Healthspan Concierge

An additional medical consultation and continuous monitoring. Interventions are reviewed and adjusted – your health strategy evolves with your data.

In-Clinic Check-inAt-Home Blood Testing

Our coaching starts with a consultation to understand results and define action steps. Optionally book ongoing support.

Fitness CoachingNutritional Guidance

70 samples from blood, stool and urine as well as living cells are cryopreserved. These biomaterials could support future developments in regenerative medicine, cell therapies or immunotherapies, depending on scientific progress.

Immune Cells Banking (PBMCs)MicrobiomeLiquid Biopsy (ccfDNA)PlasmaSerum
YEARS Klinik

7 Highlights of YEARS Evolve®

YEARS Core® – The Foundation of Our Diagnostics

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YEARS Core® – The Foundation of Our Diagnostics

Over 25 assessments and 80+ biomarkers

YEARS Core was designed from the ground up as a clinical translation of epidemiology. Drawing on evidence from some of the world's largest population studies, we reverse-engineered which diagnostics and biomarkers most reliably predict age-related disease. The result is a targeted panel of 25+ functional examinations and 80+ biomarkers that capture the earliest, silent deviations in organ, metabolic, and vascular health.

Lab diagnostics · panel register

Others quote a number. We list every marker.

Full transparency instead of “230+”. Our Ultimate panel covers 233 individual biomarkers across 9 systems, listed here in full. Pick a program and the register shows what is included.

131 markers9 systems3 programsAs of 07 · 2026
greyed= not included in Evolve® (from Ultimate up).

01Basics & blood count

55 / 55
AlbuminCalcium (ionisiert)Calcium, gesamtChloridCreatinkinase (CK)Eiweiß, gesamtKaliumLDHLipaseMagnesiumNatriumPhosphat, anorg.TransferrinLeukozytenErythrozytenHämoglobinHämatokritMCVMCHMCHCErythrozytenvert.-breiteThrombozytenNeutrophileNeutrophile absolutLymphozytenLymphozyten absolutMonozytenMonozyten absolutEosinophileEosinophile absolutBasophileBasophile absolutGranulozytenvorstufenFarbe (U)Trübung (U)pH (U)Spez. Gewicht (U)Blut (U)Leukozyten (U)Nitrit (U)Eiweiß (U)Glucose (U)Keton (U)Bilirubin (U)Urobilinogen (U)Ascorbinsäure (U)Albumin/Mikroalbumin (U)Creatinin (U)PräalbuminAlbumin (Elektroph.)Alpha-1-GlobulinAlpha-2-GlobulinBeta-GlobulinGamma-GlobulinImmunolog. Stuhltest (iFOBT)

02Liver

7 / 7
Alk. PhosphataseBilirubin, direktBilirubin, gesamtCholinesteraseGOT (AST)GPT (ALT)Gamma-GT

03Kidney

5 / 5
Creatinin (enzymatisch)Cystatin-CHarnstoffHarnsäureOsmolalität

04Cardiovascular & lipids

17 / 30
Cholesterin, gesamtLDL-CholesterinHDL-CholesterinNON-HDL-CholesterinTriglycerideApolipoprotein BLipoprotein (a)NT-proBNPHomocysteinVLDL-CholesterinLp-PLA2Oxidiertes LDLFettsäuren, freiOmega-3-IndexMR-proADMCreatinkinase-MB (CK-MB)Myoglobinα-Linolensäure (ALA)EPADHALinolsäureγ-LinolensäureBishomo-γ-LinolensäureArachidonsäureEPA/AA-QuotientBehensäure (C22:0)Lignocerinsäure (C24:0)Cerotinsäure (C26:0)PhytansäurePristansäure

05Diabetes, coagulation & infection

12 / 20
HbA1c (NGSP)HbA1c (IFCC)Glucose (nüchtern)Glucose (+1h)Glucose (+2h)InsulinHOMA-IndexFibrinogenQuick (TPZ)aPTTThrombinzeit (TZ)von-Willebrand-Diagn.HBc-AkHBe-AgHBs-AgHBs-Ak/Anti-HBHBV-DNA quant.HCV-AkHIV-1/2-Ak/p24-AgTPHA (Syphilis)

06Hormones & endocrinology

13 / 18
TSH basalFT3FT4CortisolDHEA-STestosteron, gesamtTestosteron, freiSHBGÖstradiolFSHLHProlactinIGF-1ACTHAldosteronPTH, intaktHGH/WachstumshormonPSA, gesamt

07Vitamins, micronutrients & longevity

16 / 28
Vitamin D 25-OHVitamin B12FolsäureFerritinEisenVitamin A/RetinolVitamin B1Vitamin B6Vitamin EVitamin K1Vitamin K2Jod, gesamtSelenZinkCoenzym Q10NicotinamidAdiponectinLeptinBeta-CrossLaps (CTX)CDTTMAOGDF-15Quotient pTau217expAmyloid beta 1-42expCotinin3-OH-CotininNicotinAnabasin

08Immunology & autoimmune

6 / 26
CRP high sensitiveInterleukin-6IgG TurbidimetrieIgA TurbidimetrieIgM TurbidimetrieImmunglobulin E (IgE)Antinukleäre-Ak (ANA)CCP-AktTG2-Ak IgARheumafaktor IgMc-ANCAp-ANCAMultiplex Allergietest (ALEX2)Lymphozyten, gesamtT-Lymphozyten (CD3+)T-Helferzellen (CD4+)T-Suppressorz. (CD8+)T-Zell-Ratio (CD4/CD8)B-Lymphozyten (CD19+)NK-ZellenIgG 1IgG 2IgG 3IgG 4IgA 1IgA 2

09Amino acid analysis

0 / 44
AlaninArgininAsparaginAspartatCystinGlutaminGlutamatGlycinHistidinIsoleucinLeucinLysinMethioninPhenylalaninProlinSerinThreoninTryptophanTyrosinValin1-Methylhistidin3-MethylhistidinAdenosylhomocysteinAllo-Isoleucinα-Aminoadipinsäureα-AminobuttersäureAnserinBeta-Alaninβ-AminoisobuttersäureCarnosinCitrullinCystathioninEthanolaminGABAHydroxylysinHydroxyprolinOrnithinPhosphoethanolaminPhosphoserinPipecolinsäureSaccharopinSarcosinSulfocysteinTaurin

10Additional procedures

Ultimate only · not blood markers
Whole-Genome-SequencingWhole-Exome-SequencingPharmakogenetikGanzkörper-MRTexpLiquid Biopsy / TruCheckexp

Programs are cumulative: Evolve includes all Core markers, Ultimate all Evolve markers. “EXP” marks experimental procedures still under research — details in the transparency chapter.

Frequently asked questions about YEARS Evolve

Evolve includes everything from Core and extends it in four places. First, the full-body MRI without radiation exposure, which makes structural changes visible that no blood value shows. Second, the liquid biopsy for cancer early detection via cell-free tumour DNA in the blood. Third, the extension from 89 to around 120 laboratory biomarkers. Fourth, longevity coaching and a check-in during the year, so that a finding actually turns into change rather than just a PDF. The examination day takes around nine hours instead of six. Evolve costs 7,600 euros compared with 1,900 euros for Core. Whether that difference is justified for you depends on your history, not on a wish for more data.

The MRI shows structure: masses, changes in organs, vessels and the spine, all without X-ray radiation. For some tumour types and for incidental organ findings it is highly informative. It also has clear limits. Very small tumours, changes in hollow organs such as the bowel, and cancers such as leukaemia are not reliably detected. An unremarkable MRI is therefore not an all-clear but a snapshot. Conversely, a full-body MRI finds irregularities in many people that turn out to be harmless but still cause investigation and worry. That is why we use it embedded in history-taking and the laboratory picture, not as an isolated scan, and discuss every finding with you medically.

The liquid biopsy looks for cell-free DNA in the blood that originates from tumour cells. It can pick up signals from several cancer types in one test, including some for which no established screening exists. That is the actual benefit. Context matters, though: sensitivity is considerably lower in early stages than in advanced ones, and it varies substantially by tumour type. A negative result does not rule out cancer. False positives also occur and lead to follow-up diagnostics that take a toll. These methods are still young and long-term data on survival benefit is incomplete. We therefore use the test as a complement, never as a replacement for established organ-specific screening.

The price difference is substantial, so here is an honest answer: Evolve is worth it when there is a concrete reason for the additional depth. Typically that is a family history of cancer or heart disease, an age from around 50 when the risk for many tumour types rises, or an existing irregular finding you want to place in structural context. People who notice after a Core year that implementation does not happen without guidance also benefit from the follow-ups. If you are young, symptom-free and without family history, Core gives you the most insight per euro. We will tell you that in the intro call too, even when it argues against the more expensive program.

The day is the beginning, not the result. Once all findings are in, usually within two to three weeks, the medical strategy consultation takes place. There the values become a concrete annual plan with priorities that fit your everyday life. After that, longevity coaching supports you with implementation: nutrition, training, sleep and stress. During the year a check-in follows, where we review what worked and what did not, and adjust the plan accordingly. If a finding needs further investigation, we coordinate the referral to the appropriate specialists instead of leaving you to handle it alone. Your values stay documented, so the next check-up compares trends rather than snapshots.

There's no greater return than the one you make in your own health.

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