Our most advanced preventive health program.

Ultimate includes everything from Evolve and adds four areas: medical genomics, epigenomics, microbiome analysis and experimental longevity markers. The number of laboratory biomarkers rises from around 120 to roughly 230. The second difference is the level of care. Instead of one check-in per year there are three, and you get a dedicated health manager as your point of contact, plus concierge services for coordinating follow-up appointments. The examination day takes around nine hours, as with Evolve. Ultimate costs 16,900 euros. The difference therefore lies less in any single test than in the shift from a snapshot to year-round medical oversight.

Genetic analysis reveals predispositions that blood values cannot show. Three areas are practically relevant: hereditary cancer risks such as BRCA variants, cardiovascular predispositions such as familial hypercholesterolaemia, and pharmacogenetics, meaning how your body metabolises certain medications. This information changes something concrete, because it affects screening intervals and medication choices. The limitation belongs with it: a genome is not a prognosis. Most variants shift probabilities slightly without determining anything, and many findings are of unclear significance. We therefore always discuss genetic results medically, partly because they can affect relatives and partly because German genetic diagnostics law requires counselling. You decide in advance which categories of finding you want to be told about at all.

Epigenetic clocks estimate a biological age from the methylation pattern of your DNA. Across large study populations these estimates do correlate with disease risk and mortality, and that is well established. The jump from population to individual is exactly where the market regularly overpromises. Different clocks return different values for the same sample, repeat measurement precision is limited, and there is so far no evidence that a lowered epigenetic age actually leads to a longer life. We use the value as a supplementary parameter to track over time alongside robust markers, not as a figure you should base decisions on.

The health manager is your constant point of contact across the year, so you do not have to explain your situation from scratch every time. In practice they handle three things. They coordinate appointments and follow-up diagnostics, including those with external specialists when a finding needs further investigation. They track the prevention plan and get in touch when a follow-up value is due, rather than waiting for you to remember. And they are the route to your treating physician for questions between appointments. The health manager does not replace medical judgement; clinical decisions stay with the specialist. Their job is to keep the plan from stalling in everyday life.

Ultimate is the most comprehensive program and at 16,900 euros also the most expensive, so here is a clear framing. It fits when two things come together: an actual medical reason for the additional depth, such as a relevant family history or a complex set of existing findings, and a wish for year-round guidance rather than a one-off measurement. If you mainly want to know where you stand, Core or Evolve answers that without the additional diagnostics. More markers do not automatically mean more clarity; they also mean more findings of unclear significance. If Ultimate is not right for you, we will say so in the free intro call, before you book.