Examination room at the YEARS clinic in Berlin — medical genetics within the check-up

Berlin · For patients from all over Germany

Medical genetic analysisphysician-ordered, not mail-ordered.

In Germany, predictive genomic diagnostics belong in medical hands: 170+ clinically curated risk genes via whole exome and whole genome sequencing, with genetic counselling under the Gendiagnostikgesetz. One day in Berlin, around 15 minutes from the main station.

  • 170+ risk genes
  • Whole exome & genome
  • Genetic counselling
  • Part of Ultimate

Why this matters

A genetic result is only as good as the interpretation that comes with it.

A test can be ordered online in five minutes. What comes afterwards is the problem: a list of variants, often without family history, without medical assessment and without anyone telling you what follows from it. An abnormal result without context creates anxiety. An unremarkable one suggests a safety it does not cover.

German law takes a similar view. Under the Gendiagnostikgesetz, predictive genetic testing may only be ordered by a physician and requires genetic counselling. That is not bureaucracy; it is the point at which data becomes a medical statement: what is relevant to your history, what concretely follows from it, and what explicitly does not.

Consumer genetic test

Raw data

Single variants on a chip, a PDF report, no family history, no medical assessment, no counselling. What follows from it is left for you to work out.

Physician-led genomic diagnostics

170+

Clinically curated risk genes from whole exome and whole genome sequencing, read together with your family history, with genetic counselling and a plan for what to do.

Medical results consultation at YEARS in Berlin

How we work

Sequencing is the easy part. Deciding what to report is the hard part.

  • 170+ clinically curated risk genes

    We sequence by whole exome and whole genome, but we do not report everything that is technically measurable. What gets interpreted is a clinically curated panel of more than 170 genes for which the link to a concrete disease risk is established and where something actually follows from the result.

  • Physician-ordered, with genetic counselling

    Predictive genetic diagnostics in Germany fall under the Gendiagnostikgesetz (GenDG). They may only be ordered by a physician and are tied to genetic counselling. That is our standard route, not an optional extra.

  • Family history beats panel size

    A result only becomes readable through your history. Which genes matter depends on what occurs in your family, how early, and in what pattern. Without that context a gene panel is a list of numbers.

  • A risk is not a diagnosis

    We also tell you what a result does not mean. Most risk variants are not fully penetrant: a carrier does not necessarily develop the condition. What follows from a result is a tighter screening interval or a specific work-up, not a prediction.

What gets reported

Genes from which something actually follows.

Curated by clinical relevance, not by technical feasibility. The last point matters to us as much as the first five.

Hereditary cancer risk

Genes where a pathogenic variant clearly shifts the lifetime risk for certain tumour types. A positive result changes mainly one thing: from when and how often screening happens.

Cardiovascular and lipid metabolism genes

Familial hypercholesterolaemia and related constellations often go unrecognised for decades although they are treatable. Here genetics explains why values do not come down despite a good lifestyle.

Metabolic and storage conditions

Conditions such as haemochromatosis or alpha-1 antitrypsin deficiency are rare, but where they are present the knowledge is actionable and the measures are simple.

Pharmacogenetics

How you metabolise certain active substances is partly genetically determined. This is the most immediately practical part of the result, because it affects the dosing of future medication.

Carrier status

Relevant if family planning is on the table: whether you carry variants that are inconsequential for you but not for offspring. Here too, counselling is part of the result.

What we deliberately do not report

No talent, personality or diet-type interpretations, and no polygenic scores without solid clinical validation. The evidence is too thin, and a result without a consequence is not a benefit.

Medical genetics at YEARS — sequencing and medical interpretation

Genomic diagnostics

A risk variant does not tell you that you will fall ill. It tells you where to look more closely.

How it works if you travel in

One trip, one day, results and counselling without a second journey.

01

Free intro call

Beforehand and without travelling. We go through your family history and say honestly whether genomic diagnostics add anything in your case, or whether the smaller route is enough.

02

One day in Berlin

Medical history, sample collection and the rest of the programme diagnostics in one appointment in City West, around 15 minutes from the main station. Breakfast and lunch included.

03

Sequencing and curation

Whole exome and whole genome sequencing in the laboratory, followed by medical review of the variants against the curated panel. This takes several weeks, and we tell you in advance why.

04

Genetic counselling and plan

The results consultation happens once the analysis has been reviewed, without a second trip if you prefer. The outcome is not a list of variants but an interpretation including screening intervals. You receive the report digitally.

Internal medicine assessment

Dr. med. Sebastian Kuss

Dr. med. Sebastian Kuss

Specialist in Internal Medicine

Those who have no time for their health will later need plenty of time for their illnesses.

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Choose the right checkup for you

All programs include comprehensive diagnostics and individual consultation

Core®

A medically guided baseline check that shows you where you stand and which topics need priority now.

EUR1,900
Consultation
Included
Biomarkers
89
Duration
6h
Check-ins
-

For everyone who …

  • want to truly know where they stand for the first time
  • want to go beyond the five standard values at the GP
  • want to start with prevention, without maximum depth right away

What you get

After one day you know where you are healthy and which two or three topics matter now.

Choose YEARS Core® >More Info

Evolve®

Comprehensive diagnostics plus annual plan, follow-ups and adjustments — turning insight into lasting change.

EUR7,600
Consultation
Included
Biomarkers
120
Duration
9h
Check-ins
1x

For everyone who …

  • want the full picture including whole-body MRI
  • have a family history or first irregularities
  • want to turn values into a guided annual plan

What you get

You get the full structural picture plus a plan that moves with you through the year.

Choose YEARS Evolve® >More Info

Ultimate®

Personal health management with close medical guidance, Europe's most comprehensive diagnostics and continuous oversight.

EUR16,900
Consultation
Included
Biomarkers
230
Duration
9h
Check-ins
3x

For everyone who …

  • want maximum diagnostic depth, down to epigenetics, neurology and microbiome
  • want continuous medical guidance instead of a snapshot
  • want to actively steer their healthy years, not just measure them

What you get

You have a team that steers your health year-round, instead of measuring it just once.

Choose YEARS Ultimate® >More Info

Frequently asked questions about genetic analysis

In Germany, predictive genomic diagnostics belong in medical hands: they fall under the Gendiagnostikgesetz and are tied to genetic counselling. The options are human genetics institutes and centres, specialised practices, and preventive medicine clinics that embed the analysis in a check-up. YEARS is a physician-led clinic in Berlin City West working with patients from all over Germany. The analysis is part of the Ultimate programme; sample collection and consultation take place in one day in Berlin, and the clinic is around 15 minutes from the main station.

Three things. First scope: consumer tests usually examine single variants on a chip, whereas we sequence by whole exome and whole genome and interpret more than 170 clinically curated risk genes. Second interpretation: a raw result without family history and without medical assessment is barely usable clinically. Third the legal framework: in Germany predictive genetic testing may only be ordered by a physician and requires genetic counselling. That is precisely what direct-to-consumer providers do not deliver.

That is the normal case; a large share of our patients travel in. The process is designed around a single day: medical history, sample collection and the rest of the programme diagnostics all happen at the same appointment. The clinic is in City West, around 15 minutes from the main station and easy to reach from the airport. Genetic counselling and the results consultation follow once the analysis is complete, and that can be arranged without a second trip. You receive the written report digitally.

Whole exome and whole genome sequencing take considerably longer than a standard laboratory analysis. Expect several weeks between sample collection and the complete report, depending on scope and any queries to the laboratory. The other results from your check-up are available earlier and are not held back. For the genetic part: we come back to you as soon as the analysis has been medically reviewed, and we take time for that conversation.

The clearest benefit is for people with a notable family history: several cases of the same condition, early onset, or a known variant in the family. It also makes sense when values are implausible despite a good lifestyle, or when family planning is concrete. It makes less sense if what you are mainly looking for is reassurance: an unremarkable genetic result does not rule out disease, because most conditions are not monogenic. In the intro call we say openly if we consider the benefit low in your case.

Genomic diagnostics are part of the Ultimate programme from €16,900, which additionally includes epigenetics, neurology and microbiome analysis. As a private medical service we bill according to GOÄ, so reimbursement is possible depending on your policy: privately insured patients submit the invoice to their insurer, and with occupational health insurance the annual budget applies. A binding commitment always comes from the insurer. In the free intro call we clarify in advance what scope your case actually needs.

Genetic data require particular protection and are treated accordingly. Processing is GDPR-compliant and covered by medical confidentiality. Results go to you alone, not to employers and not to insurers. The Gendiagnostikgesetz also sets clear limits here: insurers and employers may neither require predictive genetic testing nor accept its results.

Let us first establish whether it helps in your case.

Book a free intro call. We go through your family history and say honestly whether genomic diagnostics make sense.

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