YEARS vs Next Health: Which Longevity Clinic Fits You?

YEARS vs Next Health: Which Longevity Clinic Is Right for You?

Longevity medicine is evolving rapidly. More and more people want to stay healthy and highly capable for as long as possible, rather than simply live longer. Two different models have become particularly visible: physician-led preventive diagnostics and intervention-oriented health optimization.

Two prominent representatives of these models are YEARS, a physician-led longevity clinic in Berlin, and Next Health, a US-based health optimization provider headquartered in Los Angeles. Both aim to support longer, healthier lives. Their methods, programs, and care models, however, differ substantially.

This article provides a direct comparison of YEARS vs Next Health. We examine differences in diagnostics, scientific approach, pricing, care models, and target audiences. Rather than declaring one provider universally better, the goal is to give you a transparent basis for deciding which model suits your needs.

Does a physician-guided diagnostic day in Berlin, such as the YEARS Core® or YEARS Evolve® program, suit you best? Or are you looking for an intervention-oriented membership model with regular access to therapies and wellness technologies?

Overview: Who Are YEARS and Next Health?

To make an informed decision, it helps to understand the business model behind each provider.

YEARS: Physician-Led Longevity Clinic in Berlin

YEARS is a physician-led longevity clinic located in Berlin-Charlottenburg. Founded by a team of doctors, scientists, and entrepreneurs, including CEO Jürgen Mehrtens, YEARS follows a diagnostic-based approach to preventive medicine.

The YEARS philosophy is "diagnostics first." Before personalized interventions are recommended, an extensive medical baseline is established within a single day.

The resulting data, together with the patient's medical history, established risk factors, and current scientific evidence, forms the basis for an individualized prevention strategy.

YEARS also operates a "Clinic-as-a-Study" model. With client consent, anonymized data can contribute to a clinical registry designed to support research into health and ageing. YEARS is backed by Apollo Health Ventures, an investment firm focused on longevity and health.

Next Health: US Health Optimization Provider

Next Health, headquartered in Los Angeles, California, describes itself as a "Health Optimization & Longevity Center."

Its model places substantial emphasis on recurring interventions and wellness technologies. The company also uses biomarker testing and medical consultations to personalize and monitor treatment plans.

Compared with the concentrated diagnostic model used by YEARS, Next Health offers a broader range of recurring interventions through memberships and individual treatments.

According to Next Health, services include IV therapies, hormone optimization, peptide therapy, cryotherapy, hyperbaric oxygen therapy, infrared light therapy, biomarker testing, and other health optimization services.

Next Health operates numerous locations across the United States as well as a location in Dubai.

Locations & Accessibility: Berlin vs United States

Geographic location is one of the most practical differences between the two providers.

YEARS has a central location in Germany:

• Address: Joachimsthaler Str. 34, 10719 Berlin-Charlottenburg
• Accessibility: Located in Berlin City West with connections to major public transport hubs
• Languages: English- and German-speaking team
• Billing: Medical services are billed according to the German medical fee schedule, GOÄ. Depending on the individual tariff, indication, and insurer, privately insured patients may receive reimbursement for eligible medical services.

Next Health operates a growing international network.

Locations include sites in:

• California
• New York
• Florida
• Tennessee
• Hawaii
• Dubai

The primary service language is English.

Next Health largely operates through a US self-pay and membership model. German health insurance reimbursement should generally not be assumed and depends on the individual insurance contract and the specific service provided.

For European clients, geography can therefore play an important role. A one-time international visit may be manageable, while repeated medical follow-ups, annual assessments, or short-term strategy adjustments are considerably easier when the provider is geographically closer.

Diagnostics & Program Offerings Compared

One of the clearest differences between YEARS and Next Health is the structure and extent of the diagnostics offered.

YEARS: Comprehensive Diagnostics in One Day

YEARS currently offers three major programs with increasing diagnostic scope.

YEARS Core®

€1,900 | approximately 6 hours

Core® is designed to establish a broad preventive medical baseline within one day.

While a conventional routine blood test often measures a relatively limited selection of biomarkers, Core® includes more than 87 laboratory markers alongside imaging, cardiovascular testing, metabolic assessment, performance diagnostics, and other examinations.

Key components include:

• Laboratory Panel with 87+ Biomarkers: Including HOMA-related glucose and insulin assessment, ApoB, hs-CRP, Lp(a), Omega-3 Index, Vitamin D, ferritin, and other metabolic, cardiovascular, inflammatory, and nutritional markers.
• ApoB: A marker reflecting the number of circulating atherogenic lipoprotein particles.
• Cardiovascular Diagnostics: 12-lead ECG, arterial stiffness assessment, and ankle-brachial index.
• Ultrasound: Examination of the heart, abdominal organs, thyroid, and selected blood vessels.
• Metabolic Diagnostics: Oral glucose tolerance testing and assessment of glucose and insulin response.
• Pulmonary Diagnostics: Body plethysmography for detailed lung-function assessment.
• Body Composition: 3D body scan and bioimpedance analysis.
• Performance Diagnostics: Cardiopulmonary exercise testing with VO₂peak measurement.
• Heart Rate Variability: HRV measurement as an additional physiological parameter.
• AI-Supported Screening: FotoFinder skin imaging and retinal imaging using AI-supported analysis.
• Neurocognition and Senses: Neurocognitive testing, hearing assessment, and vision testing.
• Bone Health: Assessment of bone health and bone density according to the methods included in the program.

Cardiorespiratory fitness measured through exercise testing is a strong independent predictor of cardiovascular outcomes and all-cause mortality.

YEARS Evolve®

€7,600 | approximately 9 hours

Evolve® expands the diagnostic scope substantially and includes the examinations contained within Core® plus additional testing.

These include:

• Extended Laboratory Panel with 120+ Biomarkers: Including additional hormones, vitamins, inflammatory parameters, IGF-1, DHEA-S, testosterone, cortisol, and other biomarkers.
• Whole-Body MRI: Systematic structural imaging covering multiple organ systems using a defined YEARS MRI protocol.
• Liquid Biopsy: TruCheck, a multi-cancer detection blood test based on circulating tumor cells and related cell populations rather than circulating tumor DNA.
• Biological Sample Storage: Cryopreservation of multiple biological samples for potential future analyses.
• Epigenetic Age Testing: Several epigenetic clocks examining different methylation-based ageing signatures.

TruCheck is marketed as being capable of detecting signals associated with approximately 70 solid tumor types. This number describes the scope claimed for the technology and should not be interpreted as evidence that population-wide screening with the test has been proven to reduce cancer mortality.

The clinical utility of multi-cancer detection blood tests remains an active area of research. They should therefore be understood as complementary tools rather than replacements for established cancer screening programs.

Epigenetic clocks also require careful interpretation. They estimate biological ageing-related signatures based on patterns such as DNA methylation. Results vary depending on the clock used and should not be interpreted as a direct measurement of a person's "true biological age."

YEARS Ultimate®

€16,900 | approximately 9 hours

Ultimate® is the most extensive outpatient diagnostic program offered by YEARS.

It includes the components of Evolve® alongside additional testing such as:

• Laboratory Panel with 230+ Biomarkers: Including additional autoimmune, infectious disease, metabolic, cardiovascular, neurological, and experimental biomarkers.
• Medical Genetics: Whole-genome and/or other extensive genetic analyses covering medically relevant risk variants.
• Genetic Risk Assessment: Evaluation of selected genetic risks associated with cardiovascular disease, cancer, metabolic disease, and other conditions.
• Pharmacogenetics: Analysis of genetic variants that can influence the metabolism, efficacy, or tolerability of medications.
• Microbiome Analysis: Assessment of the intestinal microbiome.
• Additional Longitudinal Support: Medical follow-ups, coaching, and selected monitoring tools depending on the program structure.

The goal is to combine extensive diagnostics with longer-term medical interpretation and follow-up rather than treating individual biomarkers or genetic variants in isolation.

Next Health: Greater Focus on Recurring Interventions

Next Health offers a different structure.

Its model combines biomarker testing and medical consultations with a large portfolio of treatments and health optimization technologies.

Depending on location and program, services may include:

• IV Therapies: Intravenous formulations marketed for goals such as hydration, recovery, energy, or wellness.
• NAD+ and Related Therapies: NAD+ IV therapy and related products are prominently offered.
• Hormone Programs: Hormone testing and medically supervised hormone optimization programs.
• Peptide Therapy: Provider-guided peptide programs available within specific membership structures.
• Cryotherapy: Whole-body or localized exposure to very low temperatures.
• Hyperbaric Oxygen Therapy: Treatment involving oxygen exposure at increased atmospheric pressure.
• Infrared and Light-Based Technologies: Including infrared and red-light-related wellness technologies.
• Biomarker Testing: Laboratory testing used to assess health status and inform treatment plans.
• Medical Consultations: Provider consultations used to interpret results and personalize selected interventions.

The evidence supporting these interventions varies considerably.

Some therapies have well-established indications for specific medical conditions. Evidence supporting their routine use in healthy people specifically for longevity, anti-ageing, or broad health optimization is considerably more limited for several of these interventions.

For that reason, claims about improving lifespan, slowing biological ageing, or preventing disease should be evaluated separately for each intervention.

Diagnostics-First vs Intervention-Oriented Care

The central difference between YEARS and Next Health can be summarized as a difference in emphasis.

YEARS: Diagnostics-First

YEARS concentrates a large number of medical examinations into a structured diagnostic program.

The process generally follows this sequence:

1. Establish a medical baseline.
2. Identify measurable risk factors and abnormalities.
3. Interpret findings together with medical history and established risk factors.
4. Develop personalized recommendations.
5. Monitor selected findings longitudinally.

Recommendations may include changes to exercise, nutrition, sleep, medication, medical follow-up, or further diagnostic testing.

The intention is to establish a clinical rationale before introducing more intensive interventions.

Next Health: Intervention-Oriented Optimization

Next Health also uses diagnostics, but its overall service portfolio places greater emphasis on recurring interventions.

Biomarker testing and provider consultations can be used to personalize treatment plans and monitor progress. Clients can then access therapies such as IV infusions, hormone programs, peptides, cryotherapy, hyperbaric oxygen therapy, and other services depending on membership level and location.

For people who want regular access to these technologies, the membership structure can be attractive.

The main scientific consideration is that the evidence supporting "longevity" claims varies substantially between individual interventions.

Scientific Approach

YEARS positions itself primarily as a preventive medical and diagnostic provider.

Many of the measurements included within its programs are based on established relationships between risk factors and long-term health outcomes.

A good example is cardiorespiratory fitness.

Higher cardiorespiratory fitness is consistently associated with lower cardiovascular and all-cause mortality across large observational studies.

Recent UK Biobank research involving more than 11,000 adults also found that longitudinal increases in estimated cardiorespiratory fitness were associated with lower cardiovascular disease risk.

An annual increase of approximately 1 mL/kg/min in estimated VO₂max was associated with roughly a 15-16% lower risk of incident cardiovascular disease.

Importantly, this is an observational association. It does not prove that increasing VO₂max by exactly 1 mL/kg/min directly causes a 15-16% reduction in cardiovascular disease.

This distinction between association and causation matters when interpreting longevity research.

Next Health takes a more intervention-oriented approach.

Its model combines data collection with direct access to health optimization services. Certain interventions have clear medical indications, while the evidence supporting their use for general longevity or optimization varies.

This means that individual therapies should be evaluated according to their specific evidence base rather than assuming that every intervention marketed under the longevity umbrella has demonstrated long-term health benefits.

Pricing, Reimbursement & Care Model

The cost structures reflect the different business models.

YEARS

Current program prices:

• Core®: €1,900
• Evolve®: €7,600
• Ultimate®: €16,900

YEARS operates as a private medical provider in Germany.

Medical services are billed according to the German medical fee schedule, GOÄ. Depending on the individual insurance policy, medical indication, and service, privately insured patients may receive partial reimbursement.

Reimbursement cannot be guaranteed and varies between insurers and tariffs.

Each YEARS program includes medical interpretation of the diagnostic findings and a physician-guided strategy discussion. Higher-tier programs include additional diagnostic components and longer-term support.

Next Health

Next Health uses a mixture of individual treatment pricing and memberships.

Prices vary considerably depending on location, treatment, and membership level.

Examples include:

• Individual IV therapies
• Monthly membership fees
• Additional charges for certain medical or wellness services
• Separate diagnostic or treatment programs

For European clients, services generally need to be treated as self-pay unless their individual insurance contract explicitly provides reimbursement for treatment abroad.

Who Might YEARS Be Suitable For?

YEARS may be particularly relevant for people who:

• Live in Europe and want access to a physician-led preventive medicine provider.
• Want to establish a broad medical baseline before deciding on interventions.
• Prefer comprehensive diagnostics concentrated into a single day.
• Want cardiovascular, metabolic, imaging, functional, and laboratory diagnostics combined within one program.
• Are interested in advanced diagnostic options such as MRI, genetics, epigenetic testing, or biological sample storage.
• Want findings interpreted by physicians rather than receiving isolated laboratory results.
• Are privately insured in Germany and may be eligible for reimbursement of certain medical services depending on their tariff.

The model may be particularly practical for executives and entrepreneurs who want extensive diagnostics within a defined time period.

Who Might Next Health Be Suitable For?

Next Health may be particularly relevant for people who:

• Live close to one of its US or Dubai locations.
• Want ongoing access to health optimization therapies.
• Prefer a membership model.
• Are interested in services such as IV therapy, cryotherapy, hyperbaric oxygen therapy, hormone programs, or peptide therapy.
• Prefer recurring interventions rather than concentrating most testing into one comprehensive diagnostic day.

The suitability of specific interventions should be assessed individually based on medical indication, potential risks, costs, and the strength of the supporting evidence.

YEARS vs Next Health: Key Difference

The two companies address a similar audience but structure their services differently.

YEARS concentrates on physician-led preventive diagnostics.

The objective is to generate a broad medical baseline, identify individual risk factors, and use those findings to guide subsequent decisions.

Next Health combines health data with ongoing access to treatments and wellness technologies through a membership-oriented model.

Neither model can automatically guarantee better long-term health outcomes.

The relevant question is therefore what type of healthcare relationship you are looking for.

If your priority is first understanding cardiovascular, metabolic, structural, genetic, and functional health status before deciding what to change, the YEARS model is designed specifically around that process.

If your priority is regular access to interventions and health optimization technologies, Next Health provides a service model structured around that preference.

Conclusion: YEARS vs Next Health

YEARS and Next Health represent two different approaches to modern longevity medicine.

YEARS uses a physician-led, diagnostics-first model in Germany. Extensive laboratory testing, cardiovascular assessment, imaging, metabolic testing, performance diagnostics, and other examinations are combined to establish a medical baseline and develop an individualized prevention strategy.

Next Health offers a US-style health optimization model built around recurring access to interventions, technologies, consultations, and selected diagnostics.

For European clients seeking comprehensive physician-guided preventive diagnostics, YEARS offers a substantially broader publicly documented one-day diagnostic program than the standard diagnostic components described within Next Health's membership model.

For people primarily interested in ongoing access to therapies such as IV infusions, cryotherapy, hyperbaric oxygen therapy, hormone programs, or peptide therapy, Next Health offers a structure specifically designed around those services.

If you want to establish a comprehensive medical baseline before deciding what interventions make sense for you, YEARS Core® is the entry program.

For a non-binding conversation about which YEARS program fits your goals, you can contact the YEARS team directly.

This article is an editorial comparison and does not replace individual medical advice. Information regarding Next Health is based on publicly available information from the company. Programs, locations, services, and prices can change over time.

FAQ: Frequently Asked Questions About YEARS and Next Health

Is Next Health available in Europe?

Next Health currently operates primarily in the United States and also has a location in Dubai.

It does not currently operate a YEARS-style diagnostic clinic in Germany.

For most European clients, visiting a Next Health location therefore requires international travel.

Which YEARS program compares to a Next Health offering?

A direct comparison is difficult because the service models differ substantially.

YEARS Core® concentrates numerous laboratory, cardiovascular, metabolic, functional, and imaging examinations into a single diagnostic program.

YEARS Evolve® expands this structure with additional diagnostics such as whole-body MRI, multi-cancer detection testing, epigenetic testing, and biological sample storage.

Next Health instead combines selected diagnostics with memberships that provide ongoing access to health optimization interventions.

Does private health insurance cover YEARS?

YEARS bills medical services according to the German medical fee schedule, GOÄ.

Privately insured patients may receive reimbursement for eligible medical services depending on their individual insurance contract, tariff, diagnosis, and insurer.

Reimbursement should therefore be checked individually and cannot be guaranteed.

What is the difference between a diagnostics-first and intervention-oriented approach?

A diagnostics-first model begins with structured medical assessment before developing personalized recommendations.

The aim is to identify relevant risk factors, abnormalities, and opportunities for prevention before deciding which interventions are appropriate.

An intervention-oriented model combines selected diagnostics with more direct and recurring access to treatments and health optimization technologies.

The quality of either approach ultimately depends on the medical appropriateness of the individual tests and interventions, the evidence supporting them, and how the resulting information is interpreted.

Sources

• López-Bueno R, et al. Longitudinal changes of cardiorespiratory fitness are associated with cardiovascular disease and mortality: evidence from the UK Biobank. European Journal of Preventive Cardiology. 2026.
• Ross R, et al. Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign. Circulation. 2016;134(24).
• Mandsager K, et al. Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing. JAMA Network Open. 2018;1(6).
• Next Health. Official website, services, memberships, and location information.
• YEARS. Official website, program descriptions, diagnostic components, and pricing information.